About Me

Here is Yan-kun Chen (陈彦坤).

I specialize in Traditional Chinese Medicine (TCM), with a focus on new drug development, traditional herbal medicine research, and natural products. My passion lies in exploring the rich world of Chinese herbal remedies and contributing to the development of innovative medications.

Outside of my professional pursuits, I have a keen interest in AI art, finding joy in the intersection of technology and creativity. When I’m not immersed in the world of medicine and research, you can often find me capturing moments through photography or indulging my wanderlust with travel adventures. I believe in the power of combining ancient wisdom with modern knowledge to create a healthier and more vibrant world.

If you are interested in any aspect of me, I would love to chat and collaborate, please email me at - ketzap@qq.com

Academic Background

• Sep 2020 - June 2023: Hunan University of Chinese Medicine (PhD)
• Oct 2022 - Mar 2023: University of Karachi (Visiting scholar)
• Sep 2015 - June 2018: Hunan University of Chinese Medicine (MD)
• Sep 2010 - June 2014: Guangxi University (BEng)
  

Working Experience

• Oct 2023 - Now: Zhuhai Institute of Adcanced Technology (Post-doc)
• Jun 2018 - Aug 2020: Hunan Engineering Technology Research Center for Medicinal and Functional Food (Research Assistant)
  

Other Experience

• Volunteer work（2019）
• Red cross（2022）
• Conference speech at Tsinghua U（2023）

Scientific research skills

• Familiar with the extraction, separation, and purification methods of Chinese herbal medicines.
• Skilled in using analytical instruments such as HPLC/UPLC and triple quadrupole mass spectrometry.
• Skilled in medical experimental skills, proficient in cell experiments, animal experiments, PCR, and Wb operation methods.
• Familiar with R programming language, chemoinformatics, and possess proficiency in techniques such as molecular docking and molecular dynamics simulations.
• Familiar with the production process of traditional Chinese medicinal diet products, including: recipe selection ideas, Chinese medicine compatibility, and experimental design.
  

Journal Papers

• Exploring Fagonia cretica and Berberis lycium as α-Amylase Inhibitors: Potential Therapeutic Strategies for Diabetes Mellitus Investigated Through In Vitro and In Silico Approaches.
  Chen YK, Noor Rahman, Changan Jiang et al.
  Pharmacognosy Magazine.
  WOS: 001395675500001
  ISSN: 0973-1296
  2025 Jan 14. DOI: 10.1177/097312962412862

• Pulse signal may be a key bridge connecting cardiology and pulse diagnosis of TCM.
  Tang QF, Chen YK, Qu HY et al.
  Heliyon.
  WOS: 001311435400001
  ISSN: 2405-8440
  2024 Aug 28. DOI: 10.1016/j.heliyon.2024.e36785

• The role of mesenchymal stem cells in the treatment and pathogenesis of psoriasis.
  Chen YK, Asma’a H. Mohamed et al.
  Cytokine.
  2024 July 14. DOI: 10.1016/j.cyto.2024.156699

• Exploring the transformative impact of traditional Chinese medicine on depression: Insights from animal models.
  Yang Y, Chen YK, Xie MZ.
  World Journal of Psychiatry.
  2024 May 19. DOI: 10.5498/wjp.v14.i5.0000

• Identification of potential inhibitors targeting Ebola virus VP35 protein: a computational strategy.
  Chen YK, Reem M. Gahtani, Xie MZ et al.
  J Biomol Struct Dyn.
  2023 Dec 21. DOI: 10.1080/07391102.2023.2294384

• Hemagglutinin 3 and 8 can be the most efficient influenza subtypes for human host invasion; a comparative in silico approach.
  Al-Shuhaib, Alam S, Khan SA, Al-Shuhaib, Chen YK et al.
  J Biomol Struct Dyn.
  2023 Nov 15. DOI: 10.1080/07391102.2023.2280674.
  

• Exploring the underlying mechanisms of obesity and diabetes and the potential of Traditional Chinese Medicine: an overview of the literature.
  Chen YK, Liu TT, Teia FKF, Xie MZ
  Front Endocrinol (Lausanne)
  2023 Aug 1. DOI: 10.3389/fendo.2023.1218880.

• In Silico Identification of Natural Product-Based Inhibitors Targeting IL-1β/IL-1R Protein-Protein Interface.
  Liu TT, Chen YK, Adil M et al.
  Molecules.
  2023 Jun 21. DOI: 10.3390/molecules28134885.

• A review on the efficacy and mechanism of action of Shenkang injection against chronic kidney disease.
  Zou JJ, Zhou XT, Chen YK et al.
  Biomed Pharmacother.
  2020 Dec. DOI: 10.1016/j.biopha.2020.110833.
  

Graduate Thesis（毕业论文）

• 博士毕业论文：从TRAF3IP2/NF-κB信号通路探讨陈皮药膳茶提取物防治肥胖症的机制。
  陈彦坤 (导师: 谢梦洲)，湖南中医药大学。
• 硕士毕业论文：湖南地区正常人群阳虚质与平和质的脉诊信息特征对比研究。
  陈彦坤 (导师: 谢梦洲)，湖南中医药大学。

中文期刊

• 刘婷婷,陈彦坤,刘培,等. 润目逍遥散对干眼肝经郁热证模型小鼠角膜、泪腺组织miR-146a-5p与IRAK1/TRAF6/NF-κB信号通路的影响[J]. 中医杂志,2024,65(18):1915-1924. DOI:10.13288/j.11-2166/r.2024.18.012.
• 马一帆,宁世鸿,陈彦坤,等. 《针灸大成》中承山穴临床应用浅析[J]. 山西中医药大学学报,2022,23(3):233-235,240.
• 饶智,陈彦坤,刘斌,等. “药食同源”植物酵素研究进展[J]. 食品与发酵工业,2020,46(9):290-294.
• 陈宇奇,陈彦坤,石天爱,等. 80例不同肝功能指标体检人群脉象频域参数差异研究[J]. 亚太传统医药,2021,17(1):134-138.
• 喻心傲,瞿昊宇,陈彦坤,等. 湖南地区超重人群高血压脉象频域特征研究[J]. 湖南中医药大学学报,2020,40(6):717-721.
• 陈彦坤,刘琦,瞿浩宇,等. 气虚质健康人群寸口脉脉诊信息特征研究[J]. 湖南中医药大学学报,2018,38(3):289-291.
• 饶智,陈光宇,何群，陈彦坤,等. 基于电子舌技术与人工口尝评价相结合的羌活胜湿汤矫味技术研究[J]. 中药材,2021,44(3):658-663.
• 陈宇奇,陈彦坤,吴嘉萍,等. 64例不同肾功能指标的体检人群脉象频域参数的差异研究[J]. 时珍国医国药,2021,32(2):478-480.
• 陈彦坤,刘琦,谢梦洲. 脉诊仪的研发和脉象图分析方法的研究进展[J]. 湖南中医杂志,2018,34(12):172-174.
• 陈宇奇,陈彦坤,谢梦洲. 基于脉诊仪研究肥胖、超重人群与正常人群脉象频域特征的差异性[J]. 中国中医药现代远程教育,2023,21(19):29-32.
• 吴钰,饶智,陈彦坤,等. 基于仿生技术对不同产地当归阿魏酸含量与滋味的关联性研究[J]. 中国食物与营养,2022,28(2):37-43.
• 谢梦洲,陈彦坤,刘琦,等. 正常人群气虚质寸口脉脉图参数特征研究[C]. 日中伝统医药国际学术交流研讨会论文集. 2018:49-53.

专著

• 《图解脉诊入门到精通》编委，出版社：化学工业出版社，出版时间：2021年05月。
• 《中医脉诊临床图解》编委，出版社：化学工业出版社出版时间：2022年06月。

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